600 m² OSD Pharmaceutical Cleanroom and Cleanification HVAC System Engineering

Wolemba:Alex, Katswiri wa Zaumoyo ndi Mpweya Wamkati (IAQ)Wopanga Ma HVAC ndi Malo Otsukira:Wayne Luo, Wopanga Ma HVAC ndi Malo Oyeretsa (Wodziwika bwino mu: Uinjiniya wa Zamankhwala, zipatala, ma laboratories a BSL/PCR, ndi malo opangira zinthu zapamwamba)Yavomerezedwa ndi:Danny Chen, Mtsogoleri wa Gulu Lopanga Mpweya Wabwino ku Guangzhou Airwoods Environment Technology Co., Ltd.

Posachedwapa tamaliza ntchito yokonza zipinda zoyera komanso kupereka zida za fakitale yopanga mankhwala ya Oral Solid Dosage (OSD). Malo ogwirira ntchitowa ali ndi malo okwana masikweya mita 600 ndipo ali ndi mzere wonse wopanga mankhwala olimba, kuphatikizapo kulemera kwa zinthu, kusakaniza, kuumitsa bedi lamadzimadzi, kuphimba, kudula, ndi kulongedza matuza.

Mavuto

Kasitomalayo anafunika kukhazikitsa malo opangira zinthu mogwirizana ndi ISO 8 (Class D) pamene akukwaniritsa malamulo okhwima komanso ntchito. Mavuto awo akuluakulu anali awa:

• Kutsatira malamulo a LFDA:Kapangidwe ka malowa kanayenera kuvomerezedwa bwino ndi bungwe la Libyan Food and Drug Authority (LFDA), lomwe limatsatira miyezo yokhwima kwambiri yokhudza kuipitsidwa kwa zinthu zosiyanasiyana.

• Kuwongolera Zachilengedwe Molondola:Kupanga kwa mlingo wolimba kumakhala kovuta kwambiri chifukwa cha chinyezi. Pofuna kupewa kuti ufa usamamatire panthawi yopangira, malo okhala mkati mwa nyumba ayenera kusungidwa bwino pa 20–24°C ndi chinyezi cha 50%–60%.

• Nthawi Yogwira Ntchito Yochepa:Kasitomala anafunika mwachangu kuti ntchito yomanga ipititse patsogolo. Kugwiritsa ntchito njira yachikhalidwe yopezera makampani opanga mapulani am'deralo ndi makontrakitala angapo a zida nthawi zambiri kumatenga miyezi 4 mpaka 6 kapena kuposerapo, zomwe zingachedwetse kwambiri kutulutsidwa kwa zinthu zawo.

Mayankho Athu a Uinjiniya

1. Kukonza Mapangidwe Kuti Mutsimikizire Kuvomerezedwa kwa LFDA

Mu kupanga kwa OSD, ogwira ntchito osaganiza bwino komanso kayendetsedwe ka zinthu ndiye chifukwa chachikulu chomwe mabungwe olamulira amakana zilolezo zopangira. Gulu lathu la mainjiniya linachita kuwunika mosamala ndikukonza bwino mapulani oyamba a fakitale ya kasitomala.

Kuti tiwonetsetse kuti kafukufuku wa LFDA ndi wosavuta, takhazikitsa zosintha zitatu zofunika kwambiri pakupanga:

• Mayendedwe Osiyana a Malo Olowera:Tinapanga njira zodziyimira pawokha zolowera anthu, zipangizo zopangira, ndi zinthu zomalizidwa kuti tipewe kusokonezeka komwe kumachokera.

• Kutuluka kwa Zinyalala Zosiyana:Tinakhazikitsa njira yonyamulira zinyalala yokhayokha, kuonetsetsa kuti sizimadutsa m'malo oyera opangira zinthu kuti tipewe ngozi zowononga.

• Ma Cascades Ovuta Kusiyanitsa:Tinapanga makina olondola oyezera kuthamanga kwa mpweya m'malo oyera, kuonetsetsa kuti kuthamanga kwa mpweya m'makonde oyera kuli kokwera kuposa m'zipinda zoyezera mpweya. Izi zimapangitsa kuti mpweya uziyenda kupita kumadera omwe ali ndi chiopsezo chochepa cha kuipitsidwa, zomwe zimapangitsa kuti ufa wopachikidwa ukhale m'zipinda zawo zoyezera mpweya.

2. Kuphatikizika kwa HVAC ndi Control System Yoyeretsera Yopangidwira Makonda

Chofunika kwambiri pakupanga mlingo wolimba ndi kutentha ndi chinyezi chokhazikika. Kuti tisunge malo oyenera a 20–24°C ndi 50%–60% RH, tinasiya kugwiritsa ntchito makina oziziritsira mpweya abwino kwambiri ndipo tinapereka phukusi la zida zapadera zoyeretsera mpweya za HVAC zomwe zimagwiritsidwa ntchito pa mankhwala:

• Chigawo Chothandizira Mpweya cha DX (AHU):Chipangizo chopangidwa mwamakonda chomwe chimapereka mpweya woyenda ndi mphamvu ya 16,000 m³/h komanso mphamvu yoziziritsira ya 90kW, chokhala ndi mphamvu zowongolera kutentha komanso mphamvu zochotsa chinyezi m'thupi.

• Chipinda Chokonzetsera Madzi Panja:Imagwiritsa ntchito compressor yosinthira mphamvu kwambiri (R410A refrigerant yochezeka ndi zachilengedwe, mtundu wa pampu yotenthetsera) yomwe imasintha yokha mphamvu yake kutengera kuchuluka kwa kutentha komwe kuli mu workshop, kuonetsetsa kuti makinawo akugwira ntchito moyenera komanso mokhazikika.

• Dongosolo Lowongolera la Smart PLC:Yokhala ndi kabati yoyang'anira ya PLC yokhala ndi chophimba chokhudza cha Chingerezi chonse. Izi zimathandiza oyang'anira malo kuyang'anira ndikulemba ziwerengero zakale za kutentha ndi chinyezi nthawi yeniyeni, kukwaniritsa zofunikira zotsatirira deta pakuwunika kwa GMP.

3. Kukonzekera Mwachangu ndi Kukhazikitsa Mwaukadaulo Mkati mwa Miyezi 2-3

Pofuna kuthana ndi vuto la nthawi yochepa, tinapereka njira yolumikizirana kuyambira pakupanga mpaka kupereka zida. Poyerekeza ndi nthawi yachikhalidwe yopereka makontrakitala ang'onoang'ono am'deralo ya miyezi yoposa 4 mpaka 6, sitinangomaliza kupanga kapangidwe ka uinjiniya wa zipinda zoyera ndi kutumiza zida za HVAC mkati mwa miyezi itatu, komanso tinagwiritsa ntchito luso lathu loyankha mwachangu kuti timalize kukonzekera koyambirira ndikusonkhanitsa gulu la akatswiri omanga kuti agwirizane ndi makina pamalopo mkati mwa miyezi iwiri kapena itatu yokha. Njira yotseka iyi inathandiza kasitomala kuchepetsa nthawi yogwirira ntchito yawo ndi theka.

Zotsatira za Pulojekiti

• Chilolezo cha Fakitale Chotetezedwa:Ndondomeko yabwino kwambiri ya ogwira ntchito ndi zinthu zinagwiritsidwa ntchito bwino popereka ndemanga ya Libyan Food and Drug Authority (LFDA) pa nthawi yoyamba, zomwe zinalola kuti ntchitoyi ichitike pa nthawi yake.

• Kugwirizana Kwabwino Kwambiri ndi Dongosolo:Kupanga kapangidwe ka chipinda chotsukira ndi makina apadera oyeretsera a DX AHU monga phukusi logwirizana kunathetsa vuto lofala la kusamvana pakati pa makoma ndi ntchito zoyendetsera ma duct panthawi yomanga pamalopo.

• Wokonzeka Kwambiri Kupanga:Msonkhano wonse tsopano uli ndi mphamvu zonse zopangira mankhwala olimba motsatira malamulo okhwima a ISO 8 / Class D. Mukatsimikizira komaliza, njira yotsatirira izi ithandiza kasitomala kutumiza bwino mankhwala awo ku msika wapadziko lonse.